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Objective:The Severity of Alcohol Dependence Questionnaire (SADQ) is a self-report questionnaire to evaluate the severity of alcohol dependence. In this study, we analyzed internal consistency and factor structure of the Chinese-version of the SADQ (SADQ-C) in patients with alcohol dependence. Methods:We recruited 113 male patients with alcohol dependence to complete the SADQ-C. Internal consistency was expressed by Chronbach’s α. We did factor analysis using principal component analysis (PCA) with varimax rotation for the SADQ-C excluding the alcohol consumption section. Results: The internal consistency was very high with Chronbach’s α of 0.92. PCA shows four principal components, i.e. withdrawal relief drinking, affective withdrawal signs, physical withdrawal signs, and reinstatement of withdrawal symptoms following abstinence. Conclusion: The SADQ-C is a reliable instrument for alcohol dependence severity assessment in Taiwan and it can be used to monitor the treatment outcome in male patients with alcohol dependence.