Past Issues
Mirtazapine for Major Depressive Disorder with Severe Nausea and
Vomiting Secondary to Diabetic Gastroparesis
Meng-Chang Tsai, Jian-An Su
Objective: We report a case of a patient with major depressive disorder caused
by diabetic gastroparesis-related severe nausea and vomiting. Case Report: The
patient responded poorly to prokinetic agents, but her symptoms, such as depression,
nausea/vomiting, were improved after the prokinetic agents were combined
with mirtazapine. She was discharged in a stable condition and kept receiving mirtazapine.
She did not show any recurrent depression, and diabetic gastroparesisrelated
severe nausea and vomiting during follow-up. Conclusion: This is the fi rst
case report to show that mirtazapine may be effective for treating and preventing
recurrent depression caused by diabetic gastroparesis-related severe nausea and
vomiting.
by diabetic gastroparesis-related severe nausea and vomiting. Case Report: The
patient responded poorly to prokinetic agents, but her symptoms, such as depression,
nausea/vomiting, were improved after the prokinetic agents were combined
with mirtazapine. She was discharged in a stable condition and kept receiving mirtazapine.
She did not show any recurrent depression, and diabetic gastroparesisrelated
severe nausea and vomiting during follow-up. Conclusion: This is the fi rst
case report to show that mirtazapine may be effective for treating and preventing
recurrent depression caused by diabetic gastroparesis-related severe nausea and
vomiting.
| Key Word | diabetic gastroparesis, mirtazapine, depression, vomiting |
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