Past Issues
Trazodone Is Not as Effective as Other Antidepressants in Treating a Patient with Major Depressive Disorder
Kah Kheng Goh, Weng-Kin Tam, Winston W. Shen
Background: Trazodone in clinical use is ineffective because of its sedation
to let patient receive an adequate dose for treating a patient with major depressive
disorder. We are report a case report to demonstrate this clinical efficacy issue in
the treatment with trazodone. Case Report: A 83-year old male Taiwanese patient
had suffered from MDD for six months. He did not response to the treatment of
trazodone 150 mg/day for four months, but consequently, he responded to the
treatment of milnacipran 100 mg/day or mirtazapine 30 mg/day. Conclusion: Psychiatrists
in Taiwan should be alert to the fact that trazodone is not as effective as
other antidepressants, and that trazodone should not be prescribed as a single antidepressant
in treating an MDD patient.
| Key Word | antidepressant therapy, suicide, venlafaxine, bupropion |
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