Past Issues

Major Depressive Episode Comorbid with Parkinson’s Disease: A Report of Three Cases

Kuan-Chiao Lee, Yung-Chieh Yen

Case 1
A 65-year-old married male patient with a past history of coronary artery disease and benign prostatic hyperplasia, was diagnosed with major depressive disorder and generalized anxiety disorder four years ago. He was hospitalized due to depressive mood, epigastralgia, insomnia, social withdrawal, decreased appetite, and recent body weight loss. He also showed masked facial expression, resting tremors, festinating gaits, and being bed-ridden requiring help in getting out of bed. A neurologist was consulted. The image of his brain [99mTc] TRODAT-1 examination was compatible to the finding of PD, stage V.

Case 2
A 59-year-old married male patient with past history of major depressive disorder diagnosed at age 52 years, experienced diminished appetite with body weight loss, anhedonia, social withdrawal, poor concentration due to absent-minded-ness, depressed mood with suicidal ideation, uncontrollable crying, and negative thinking for more than one week. Recently, his family also observed his poker-face expression, tremors in four extremities, festinating gaits, and accidental falls. He was hospitalized and a neurologist was consulted. The picture of brain [99mTc] TRODAT-1 examination was consistent with that of PD, stage III.

Case 3
A 56-year-old widowed patient suffered from depressed mood, suicidal ideation, social withdrawal, poor memory, poor sleep quality, and decreased activities of daily living following the death of her husband two years previously. Additional symptoms included resting tremors in her hands (especially left side), mask-like facial expression and impaired motor coordination. She sought help at our neurology clinic. The finding of a brain [99mTc] TRODAT-1 study was compatible to that of PD, stage 1. Later, she was referred for psychiatric inpatient hospitalization.

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Editorial Committe, Taiwanese Journal of Psychiatry
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