Past Issues
The Prescriptions of Antipsychotic Polypharmacy and Antiparkinson Drugs Have Been Changed in Psychiatric Practice
Si-Sheng Huang
Antipsychotic polypharmacy (APP) is de-
fined as the concomitant use of two or more anti-
psychotic drugs in a patient for the treatment of a
disorder. Under certain circumstances, antipsy-
chotic co-treatment may be superior to antipsy-
chotic monotherapy regarding all-cause discon-
tinuation and general measures of efficacy [1]. In
the present issue of the Taiwanese Journal of
Psychiatry, Wu et al. [2] reported that 38.7% of
patients hospitalized with a diagnosis of schizo-
phrenia are prescribed with a combination of anti-
psychotic drugs, and that the combination of a
first-generation antipsychotic (FGA) drug and a
second-generation antipsychotic (SGA) drug
(25% of all prescribing patterns) is the most com-
monly prescribed treatment. The clinical practice
to prescribe antipsychotic drugs has been changed
in recent years.
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