Past Issues

Valproate-olanzapine-nifedipine Interaction Related Pedal Edema

Yu-Shi Lu, Ching-Hua Lin, Li-Shiu Chou

A 45-year-old single male patient with bipo-lar I disorder was admitted to acute ward of our hospital due to depressive mood with irritability for more than one month. The finding of physical examination at admission revealed no bilateral pedal edema under long-term usage of valproate 700 mg/day as mood stabilizer, nifedipine 30 mg/ day for essential hypertension, and allopurinol 100 mg/day for gouty arthritis before hospitaliza-tion. The results of laboratory tests for electro-lytes, renal function, liver function, chest X-ray, and electrocardiography were also within normal limits.
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Editorial Committe, Taiwanese Journal of Psychiatry
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