Past Issues

Differences in Electrocardiographic Findings between Oder Adult Patients with Bipolar Disorder and Schizophrenia

Pao-Huan Chen, Shang-Ying Tsai, Meng-Ling Chen, Kuo-Hsuan Chung, Shou-Hung Huang

Objective: We intended to compare the standard 12-lead electrocardiogram (ECG) recordings in older patients with bipolar disorder (BD) and schizophrenia (SZ). Methods: We recruited 109 outpatients who were aged over 50 years and had a diagnosis of BD-I or SZ. A board-certifi ed cardiologist who was blinded to clinical information, analyzed the 12-lead ECG recordings. Clinical data were obtained using interview and chart review. Results: We recruited 44 patients with BD and 65 patients with SZ. We found that signifi cantly higher proportion of BD patients had ECG-defi ned left ventricular hypertrophy than that in SZ patients (13.6% vs. 3.1%, p < 0.05). In addition, patients with BD had signifi cantly higher diastolic blood pressure and body mass index on the day of the most recent psychiatric admission than did those with SZ. Conclusion: Patients with BD are at a greater risk of ECG-defi ned left ventricular hypertrophy which may link to the unfavorable psychopathological and pathophysiological outcomes of BD itself.
Key Word bipolar disorder, schizophrenia, electrocardiogram, left ventricular hypertrophy
Editorial Committe, Taiwanese Journal of Psychiatry
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